Cargando…

Internalization of B Cell Receptors in Human EU12 μHC(+) Immature B Cells Specifically Alters Downstream Signaling Events

It has been recognized for a long time that engagement of B cell antigen receptors (BCRs) on immature B cells or mature B cells leads to completely opposite cell fate decisions. The underlying mechanism remains unclear. Here, we show that crosslinking of BCRs on human EU12 μHC(+) immature B cells re...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jing, Xie, Wanqin, Lange, Miles D., Hong, Sang Yong, Su, Kaihong, Zhang, Zhixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809603/
https://www.ncbi.nlm.nih.gov/pubmed/24222917
http://dx.doi.org/10.1155/2013/807240