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Human Leptin Protein Induces Proliferation of A549 Cells via Inhibition of PKR-Like ER Kinase and Activating Transcription Factor-6 Mediated Apoptosis
PURPOSE: To investigate the anti-apoptotic mechanism of leptin in non-small cell lung cancer. MATERIALS AND METHODS: The influences of leptin on apoptosis were investigated, analyzing the mechanism that triggers growth of A549 cells. The effects of leptin on cell proliferation were examined by XTT a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Yonsei University College of Medicine
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809871/ https://www.ncbi.nlm.nih.gov/pubmed/24142645 http://dx.doi.org/10.3349/ymj.2013.54.6.1407 |