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Duplex Reverse-Hybridization Assay for The Simultaneous Detection of KRAS/BRAF Mutations in FFPE-extracted Genomic DNA from Colorectal Cancer Specimens

We report the performance evaluation of a non-quantitative reverse-hybridization assay (KRAS-BRAF StripAssay) designed for the simultaneous detection of 10 mutations in codons 12 and 13 of the KRAS gene and BRAF mutation V600E. Dilution experiments using DNA from tumor cell lines or from formalin-fi...

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Detalles Bibliográficos
Autores principales: Buxhofer-Ausch, Veronika, Ausch, Christoph, Zeillinger, Robert, Oberkanins, Christian, Dandachi, Nadia, Reiner-Concin, Angelika, Kriegshäuser, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810114/
https://www.ncbi.nlm.nih.gov/pubmed/23324583
http://dx.doi.org/10.3233/DMA-120960