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OC125, M11 and OV197 Epitopes Are Not Uniformly Distributed in the Tandem-Repeat Region of CA125 and Require the Entire SEA Domain

The human cancer antigen 125 (CA125) is over-expressed in epithelial ovarian cancer cells and it plays a role in the pathogenesis of ovarian cancer. This protein presents a repeat region containing up to sixty tandem repeat units. The anti-CA125 monoclonal antibodies have been previously classified...

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Detalles Bibliográficos
Autores principales: Bressan, Alessandro, Bozzo, Francesca, Maggi, Carlo Alberto, Binaschi, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810124/
https://www.ncbi.nlm.nih.gov/pubmed/23396293
http://dx.doi.org/10.3233/DMA-130968