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OC125, M11 and OV197 Epitopes Are Not Uniformly Distributed in the Tandem-Repeat Region of CA125 and Require the Entire SEA Domain
The human cancer antigen 125 (CA125) is over-expressed in epithelial ovarian cancer cells and it plays a role in the pathogenesis of ovarian cancer. This protein presents a repeat region containing up to sixty tandem repeat units. The anti-CA125 monoclonal antibodies have been previously classified...
Autores principales: | Bressan, Alessandro, Bozzo, Francesca, Maggi, Carlo Alberto, Binaschi, Monica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810124/ https://www.ncbi.nlm.nih.gov/pubmed/23396293 http://dx.doi.org/10.3233/DMA-130968 |
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