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Fatty Acids are Key in 4-Hydroxy-2-Nonenal-Mediated Activation of Uncoupling Proteins 1 and 2

The production of reactive oxygen species (ROS) in mitochondria is very sensitive to the proton motive force and may be decreased by mild uncoupling, mediated e.g. by mitochondrial uncoupling proteins (UCPs). UCPs were conversely hypothesized to be activated by ROS. Conclusions from experiments stud...

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Detalles Bibliográficos
Autores principales: Malingriaux, Elena A., Rupprecht, Anne, Gille, Lars, Jovanovic, Olga, Jezek, Petr, Jaburek, Martin, Pohl, Elena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810126/
https://www.ncbi.nlm.nih.gov/pubmed/24204965
http://dx.doi.org/10.1371/journal.pone.0077786