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Variation in Cell Signaling Protein Expression May Introduce Sampling Bias in Primary Epithelial Ovarian Cancer

Although the expression of cell signaling proteins is used as prognostic and predictive biomarker, variability of protein levels within tumors is not well studied. We assessed intratumoral heterogeneity of protein expression within primary ovarian cancer. Full-length proteins were extracted from 88...

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Detalles Bibliográficos
Autores principales: Mittermeyer, Gabriele, Malinowsky, Katharina, Beese, Christian, Höfler, Heinz, Schmalfeldt, Barbara, Becker, Karl-Friedrich, Avril, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810127/
https://www.ncbi.nlm.nih.gov/pubmed/24204986
http://dx.doi.org/10.1371/journal.pone.0077825