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Substrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6

The p21-activated kinases (PAKs) are important effectors of Rho-family small GTPases. The PAK family consists of two groups, type I and type II, which have different modes of regulation and signaling. PAK6, a type II PAK, influences behavior and locomotor function in mice and has an ascribed role in...

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Detalles Bibliográficos
Autores principales: Gao, Jia, Ha, Byung Hak, Lou, Hua Jane, Morse, Elizabeth M., Zhang, Rong, Calderwood, David A., Turk, Benjamin E., Boggon, Titus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810134/
https://www.ncbi.nlm.nih.gov/pubmed/24204982
http://dx.doi.org/10.1371/journal.pone.0077818