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Quantification of Plasma Cell-Free DNA(1) in Predicting Therapeutic Efficacy of Sorafenib on Metastatic Clear Cell Renal Cell Carcinoma

PURPOSE: The objective of this study is to determine whether or not plasma cfDNA levels can predict efficacy of sorafenib in patient with metastatic cRCC. MATERIALS AND METHODS: Plasma cfDNA levels were quantified by quantitative real-time PCR at six different time-points (before treatment, 4 weeks,...

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Detalles Bibliográficos
Autores principales: Feng, Gang, Ye, Xiaobing, Fang, Fang, Pu, Chun, Huang, Houbao, Li, Guorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810240/
https://www.ncbi.nlm.nih.gov/pubmed/23324577
http://dx.doi.org/10.3233/DMA-120950