RSK Activation of Translation Factor eIF4B Drives Abnormal Increases of Laminin γ2 and MYC Protein during Neoplastic Progression to Squamous Cell Carcinoma

Overexpression of the basement membrane protein Laminin γ2 (Lamγ2) is a feature of many epidermal and oral dysplasias and all invasive squamous cell carcinomas (SCCs). This abnormality has potential value as an immunohistochemical biomarker of premalignancy but its mechanism has remained unknown. We...

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Detalles Bibliográficos
Autores principales: Degen, Martin, Barron, Patricia, Natarajan, Easwar, Widlund, Hans R., Rheinwald, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810258/
https://www.ncbi.nlm.nih.gov/pubmed/24205356
http://dx.doi.org/10.1371/journal.pone.0078979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810258/
https://www.ncbi.nlm.nih.gov/pubmed/24205356
http://dx.doi.org/10.1371/journal.pone.0078979

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