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Identification of DLEC1 D215N Somatic Mutation in Formalin Fixed Paraffin Embedded Melanoma and Melanocytic Nevi Specimens

DLEC1 has been suggested as a tumor suppressor gene in several cancers. DLEC1 D215N somatic mutation (COSM36702) was identified in a melanoma cell line through whole genome sequencing. However, little is known about the implication and prevalence of this mutation in primary melanomas or in melanocyt...

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Detalles Bibliográficos
Autores principales: Vieira, Ricardo, Simões, Maria José, Carmona, Susana, Egas, Conceição, Faro, Carlos, Figueiredo, Américo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810429/
https://www.ncbi.nlm.nih.gov/pubmed/24222856
http://dx.doi.org/10.1155/2013/469671