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In Silico Risk Assessment of HLA-A*02:06-Associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Caused by Cold Medicine Ingredients

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe drug hypersensitivities with high mortality. Typical over-the-counter drugs of cold medicines are suggested to be causative. As multiple ingredients are generally contained in cold medicines, it is of particular interest...

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Detalles Bibliográficos
Autores principales: Isogai, Hideto, Miyadera, Hiroko, Ueta, Mayumi, Sotozono, Chie, Kinoshita, Shigeru, Tokunaga, Katsushi, Hirayama, Noriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810500/
https://www.ncbi.nlm.nih.gov/pubmed/24285954
http://dx.doi.org/10.1155/2013/514068