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Evaluation of the Expression of C-kit (CD117) in Ependymomas and Oligodendrogliomas

C-kit is a proto-oncogene located on the long arm of chromosome 4. Its product, CD117, is a specific immunohistochemical (IHQ) marker that is associated with response to a potent tyrosine kinase inhibitor therapy with STI-571 (Gleevec®) in chronic myelogenous leukemia and GISTs. In our study, we aim...

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Detalles Bibliográficos
Autores principales: Zavalhia, Lisiane Silveira, Romitti, Mirian, Netto, Gabriel Corteze, dos Santos, Giovana Tavares, Meurer, Rosalva Thereza, Hilbig, Arlete, Michalowski, Mariana Bohns, Ribeiro, Marlise de Castro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810688/
https://www.ncbi.nlm.nih.gov/pubmed/22846208
http://dx.doi.org/10.3233/DMA-2012-0905