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Genetic Association and Gene-gene interaction of HAS2, HABP1 and HYAL3 Implicate Hyaluronan Metabolic Genes in Glaucomatous Neurodegeneration

Hyaluronan (HA) plays a significant role in maintaining aqueous humor outflow in trabecular meshwork, the primary ocular tissue involved in glaucoma. We examined potential association of the single nucleotide polymorphisms (SNPs) of the HA synthesizing gene – hyaluronan synthase 2 (HAS2), hyaluronan...

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Detalles Bibliográficos
Autores principales: Basu, Kaustuv, Sen, Abhijit, Ray, Kunal, Ghosh, Ilora, Datta, Kasturi, Mukhopadhyay, Arijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810698/
https://www.ncbi.nlm.nih.gov/pubmed/22960332
http://dx.doi.org/10.3233/DMA-2012-0915