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SAMstrt: statistical test for differential expression in single-cell transcriptome with spike-in normalization

Motivation: Recent transcriptome studies have revealed that total transcript numbers vary by cell type and condition; therefore, the statistical assumptions for single-cell transcriptome studies must be revisited. SAMstrt is an extension code for SAMseq, which is a statistical method for differentia...

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Detalles Bibliográficos
Autores principales: Katayama, Shintaro, Töhönen, Virpi, Linnarsson, Sten, Kere, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810855/
https://www.ncbi.nlm.nih.gov/pubmed/23995393
http://dx.doi.org/10.1093/bioinformatics/btt511