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SAMstrt: statistical test for differential expression in single-cell transcriptome with spike-in normalization
Motivation: Recent transcriptome studies have revealed that total transcript numbers vary by cell type and condition; therefore, the statistical assumptions for single-cell transcriptome studies must be revisited. SAMstrt is an extension code for SAMseq, which is a statistical method for differentia...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810855/ https://www.ncbi.nlm.nih.gov/pubmed/23995393 http://dx.doi.org/10.1093/bioinformatics/btt511 |