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Using Molecular Features of Xenobiotics to Predict Hepatic Gene Expression Response

[Image: see text] Despite recent advances in molecular medicine and rational drug design, many drugs still fail because toxic effects arise at the cellular and tissue level. In order to better understand these effects, cellular assays can generate high-throughput measurements of gene expression chan...

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Detalles Bibliográficos
Autores principales: Fernald, Guy Haskin, Altman, Russ B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810861/
https://www.ncbi.nlm.nih.gov/pubmed/24010729
http://dx.doi.org/10.1021/ci3005868