Postconditioning ameliorates mitochondrial DNA damage and deletion after renal ischemic injury

BACKGROUND: Reactive oxygen species (ROS) play a major role in causing injury in ischemia-reperfusion (I/R). Mitochondrial DNA (mtDNA) is particularly vulnerable to oxidative damage. We propose that increased mitochondrial ROS production is likely to damage mtDNA, causing further injury to mitochond...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Xiaohua, Zhang, Lei, Jiang, Yunpeng, Yang, Yujia, Zhang, Wenqi, Li, Yulin, Zhang, Xiuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811057/
https://www.ncbi.nlm.nih.gov/pubmed/24021677
http://dx.doi.org/10.1093/ndt/gft278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811057/
https://www.ncbi.nlm.nih.gov/pubmed/24021677
http://dx.doi.org/10.1093/ndt/gft278

Ejemplares similares