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Pharmacokinetic Properties of Artemether, Dihydroartemisinin, Lumefantrine, and Quinine in Pregnant Women with Uncomplicated Plasmodium falciparum Malaria in Uganda

Pregnancy alters the pharmacokinetic properties of many drugs used in the treatment of malaria, usually resulting in lower drug exposures. This increases the risks of treatment failure, adverse outcomes for the fetus, and the development of resistance. The pharmacokinetic properties of artemether an...

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Detalles Bibliográficos
Autores principales: Tarning, Joel, Kloprogge, Frank, Dhorda, Mehul, Jullien, Vincent, Nosten, Francois, White, Nicholas J., Guerin, Philippe J., Piola, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811434/
https://www.ncbi.nlm.nih.gov/pubmed/23917320
http://dx.doi.org/10.1128/AAC.00683-13