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The PR/SET Domain Zinc Finger Protein Prdm4 Regulates Gene Expression in Embryonic Stem Cells but Plays a Nonessential Role in the Developing Mouse Embryo

Prdm4 is a highly conserved member of the Prdm family of PR/SET domain zinc finger proteins. Many well-studied Prdm family members play critical roles in development and display striking loss-of-function phenotypes. Prdm4 functional contributions have yet to be characterized. Here, we describe its w...

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Detalles Bibliográficos
Autores principales: Bogani, Debora, Morgan, Marc A. J., Nelson, Andrew C., Costello, Ita, McGouran, Joanna F., Kessler, Benedikt M., Robertson, Elizabeth J., Bikoff, Elizabeth K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811882/
https://www.ncbi.nlm.nih.gov/pubmed/23918801
http://dx.doi.org/10.1128/MCB.00498-13