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Correction of Chloride Transport and Mislocalization of CFTR Protein by Vardenafil in the Gastrointestinal Tract of Cystic Fibrosis Mice

Although lung disease is the major cause of mortality in cystic fibrosis (CF), gastrointestinal (GI) manifestations are the first hallmarks in 15–20% of affected newborns presenting with meconium ileus, and remain major causes of morbidity throughout life. We have previously shown that cGMP-dependen...

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Detalles Bibliográficos
Autores principales: Dhooghe, Barbara, Noël, Sabrina, Bouzin, Caroline, Behets-Wydemans, Gaëtane, Leal, Teresinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811977/
https://www.ncbi.nlm.nih.gov/pubmed/24204804
http://dx.doi.org/10.1371/journal.pone.0077314