Exendin-4 Protects Mitochondria from Reactive Oxygen Species Induced Apoptosis in Pancreatic Beta Cells

OBJECTIVE: Mitochondrial oxidative stress is the basis for pancreatic β-cell apoptosis and a common pathway for numerous types of damage, including glucotoxicity and lipotoxicity. We cultivated mice pancreatic β-cell tumor Min6 cell lines in vitro and observed pancreatic β-cell apoptosis and changes...

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Detalles Bibliográficos
Autores principales: Li, Zhen, Zhou, Zhiguang, Huang, Gan, Hu, Fang, Xiang, Yufei, He, Lining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811987/
https://www.ncbi.nlm.nih.gov/pubmed/24204601
http://dx.doi.org/10.1371/journal.pone.0076172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811987/
https://www.ncbi.nlm.nih.gov/pubmed/24204601
http://dx.doi.org/10.1371/journal.pone.0076172

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