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Beta-Cell ARNT Is Required for Normal Glucose Tolerance in Murine Pregnancy

AIMS: Insulin secretion increases in normal pregnancy to meet increasing demands. Inability to increase beta-cell function results in gestational diabetes mellitus (GDM). We have previously shown that the expression of the transcription factor ARNT (Aryl-hydrocarbon Receptor Nuclear Translocator) is...

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Detalles Bibliográficos
Autores principales: Lau, Sue Mei, Cha, Kuan Minn, Karunatillake, Ayesha, Stokes, Rebecca A., Cheng, Kim, McLean, Mark, Cheung, N. W., Gonzalez, Frank J., Gunton, Jenny E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812008/
https://www.ncbi.nlm.nih.gov/pubmed/24204824
http://dx.doi.org/10.1371/journal.pone.0077419