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The Development of a Specific and Sensitive LC-MS-Based Method for the Detection and Quantification of Hydroperoxy- and Hydroxydocosahexaenoic Acids as a Tool for Lipidomic Analysis

Docosahexaenoic acid (DHA) is an n-3 polyunsaturated fatty acid that is highly enriched in the brain, and the oxidation products of DHA are present or increased during neurodegenerative disease progression. The characterization of the oxidation products of DHA is critical to understanding the roles...

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Detalles Bibliográficos
Autores principales: Derogis, Priscilla B. M. C., Freitas, Florêncio P., Marques, Anna S. F., Cunha, Daniela, Appolinário, Patricia P., de Paula, Fernando, Lourenço, Tiago C., Murgu, Michael, Di Mascio, Paolo, Medeiros, Marisa H. G., Miyamoto, Sayuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812029/
https://www.ncbi.nlm.nih.gov/pubmed/24204871
http://dx.doi.org/10.1371/journal.pone.0077561