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Viral Interference with DNA Repair by Targeting of the Single-Stranded DNA Binding Protein RPA
Correct repair of damaged DNA is critical for genomic integrity. Deficiencies in DNA repair are linked with human cancer. Here we report a novel mechanism by which a virus manipulates DNA damage responses. Infection with murine polyomavirus sensitizes cells to DNA damage by UV and etoposide. Polyoma...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812037/ https://www.ncbi.nlm.nih.gov/pubmed/24204272 http://dx.doi.org/10.1371/journal.ppat.1003725 |