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Genomic and Transcriptional Alterations in Lung Adenocarcinoma in Relation to EGFR and KRAS Mutation Status

INTRODUCTION: In lung adenocarcinoma, the mutational spectrum is dominated by EGFR and KRAS mutations. Improved knowledge about genomic and transcriptional alterations in and between mutation-defined subgroups may identify genes involved in disease development or progression. METHODS: Genomic profil...

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Detalles Bibliográficos
Autores principales: Planck, Maria, Edlund, Karolina, Botling, Johan, Micke, Patrick, Isaksson, Sofi, Staaf, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812039/
https://www.ncbi.nlm.nih.gov/pubmed/24205279
http://dx.doi.org/10.1371/journal.pone.0078614