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A Comprehensive Survey of Small-Molecule Binding Pockets in Proteins

Many biological activities originate from interactions between small-molecule ligands and their protein targets. A detailed structural and physico-chemical characterization of these interactions could significantly deepen our understanding of protein function and facilitate drug design. Here, we pre...

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Detalles Bibliográficos
Autores principales: Gao, Mu, Skolnick, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812058/
https://www.ncbi.nlm.nih.gov/pubmed/24204237
http://dx.doi.org/10.1371/journal.pcbi.1003302