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Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice
β-defensin peptides are a family of antimicrobial peptides present at mucosal surfaces, with the main site of expression under normal conditions in the male reproductive tract. Although they kill microbes in vitro and interact with immune cells, the precise role of these genes in vivo remains uncert...
Autores principales: | Zhou, Yu S., Webb, Sheila, Lettice, Laura, Tardif, Steve, Kilanowski, Fiona, Tyrrell, Christine, MacPherson, Heather, Semple, Fiona, Tennant, Peter, Baker, Tina, Hart, Alan, Devenney, Paul, Perry, Paul, Davey, Tracey, Barran, Perdita, Barratt, Chris L., Dorin, Julia R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812073/ https://www.ncbi.nlm.nih.gov/pubmed/24204287 http://dx.doi.org/10.1371/journal.pgen.1003826 |
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