Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice

β-defensin peptides are a family of antimicrobial peptides present at mucosal surfaces, with the main site of expression under normal conditions in the male reproductive tract. Although they kill microbes in vitro and interact with immune cells, the precise role of these genes in vivo remains uncert...

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Detalles Bibliográficos
Autores principales: Zhou, Yu S., Webb, Sheila, Lettice, Laura, Tardif, Steve, Kilanowski, Fiona, Tyrrell, Christine, MacPherson, Heather, Semple, Fiona, Tennant, Peter, Baker, Tina, Hart, Alan, Devenney, Paul, Perry, Paul, Davey, Tracey, Barran, Perdita, Barratt, Chris L., Dorin, Julia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812073/
https://www.ncbi.nlm.nih.gov/pubmed/24204287
http://dx.doi.org/10.1371/journal.pgen.1003826