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A Reversible Histone H3 Acetylation Cooperates with Mismatch Repair and Replicative Polymerases in Maintaining Genome Stability

Mutations are a major driving force of evolution and genetic disease. In eukaryotes, mutations are produced in the chromatin environment, but the impact of chromatin on mutagenesis is poorly understood. Previous studies have determined that in yeast Saccharomyces cerevisiae, Rtt109-dependent acetyla...

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Detalles Bibliográficos
Autores principales: Kadyrova, Lyudmila Y., Mertz, Tony M., Zhang, Yu, Northam, Matthew R., Sheng, Ziwei, Lobachev, Kirill S., Shcherbakova, Polina V., Kadyrov, Farid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812082/
https://www.ncbi.nlm.nih.gov/pubmed/24204308
http://dx.doi.org/10.1371/journal.pgen.1003899