Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B

The evolution of drug resistance in microbial pathogens provides a paradigm for investigating evolutionary dynamics with important consequences for human health. Candida albicans, the leading fungal pathogen of humans, rapidly evolves resistance to two major antifungal classes, the triazoles and ech...

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Detalles Bibliográficos
Autores principales: Vincent, Benjamin Matteson, Lancaster, Alex Kelvin, Scherz-Shouval, Ruth, Whitesell, Luke, Lindquist, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812114/
https://www.ncbi.nlm.nih.gov/pubmed/24204207
http://dx.doi.org/10.1371/journal.pbio.1001692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812114/
https://www.ncbi.nlm.nih.gov/pubmed/24204207
http://dx.doi.org/10.1371/journal.pbio.1001692

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