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Reconstruction and Analysis of Transcription Factor–miRNA Co-Regulatory Feed-Forward Loops in Human Cancers Using Filter-Wrapper Feature Selection

BACKGROUND: As one of the most common types of co-regulatory motifs, feed-forward loops (FFLs) control many cell functions and play an important role in human cancers. Therefore, it is crucial to reconstruct and analyze cancer-related FFLs that are controlled by transcription factor (TF) and microRN...

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Detalles Bibliográficos
Autores principales: Peng, Chen, Wang, Minghui, Shen, Yi, Feng, Huanqing, Li, Ao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812136/
https://www.ncbi.nlm.nih.gov/pubmed/24205155
http://dx.doi.org/10.1371/journal.pone.0078197