Dmp1α Inhibits HER2/neu-Induced Mammary Tumorigenesis

Our recent study shows a pivotal role of Dmp1 in quenching hyperproliferative signals from HER2 to the Arf-p53 pathway as a safety mechanism to prevent breast carcinogenesis. To directly demonstrate the role of Dmp1 in preventing HER2/neu-driven oncogenic transformation, we established Flag-Dmp1α tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Fry, Elizabeth A., Taneja, Pankaj, Maglic, Dejan, Zhu, Sinan, Sui, Guangchao, Inoue, Kazushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812138/
https://www.ncbi.nlm.nih.gov/pubmed/24205004
http://dx.doi.org/10.1371/journal.pone.0077870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812138/
https://www.ncbi.nlm.nih.gov/pubmed/24205004
http://dx.doi.org/10.1371/journal.pone.0077870

Ejemplares similares