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Complex Relationship between Mismatch Repair Proteins and MBD4 during Immunoglobulin Class Switch Recombination
Mismatch repair (MMR) safeguards against genomic instability and is required for efficient Ig class switch recombination (CSR). Methyl CpG binding domain protein 4 (MBD4) binds to MutL homologue 1 (MLH1) and controls the post-transcriptional level of several MMR proteins, including MutS homologue 2...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812156/ https://www.ncbi.nlm.nih.gov/pubmed/24205214 http://dx.doi.org/10.1371/journal.pone.0078370 |