Complex Relationship between Mismatch Repair Proteins and MBD4 during Immunoglobulin Class Switch Recombination

Mismatch repair (MMR) safeguards against genomic instability and is required for efficient Ig class switch recombination (CSR). Methyl CpG binding domain protein 4 (MBD4) binds to MutL homologue 1 (MLH1) and controls the post-transcriptional level of several MMR proteins, including MutS homologue 2...

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Detalles Bibliográficos
Autores principales: Grigera, Fernando, Bellacosa, Alfonso, Kenter, Amy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812156/
https://www.ncbi.nlm.nih.gov/pubmed/24205214
http://dx.doi.org/10.1371/journal.pone.0078370

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