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Critical Role of TLR4 in Human Metapneumovirus Mediated Innate Immune Responses and Disease Pathogenesis

Human metapneumovirus (hMPV) is one of the main causes of acute respiratory tract infections in children, elderly and immunocompromised patients. The mammalian Toll-like receptors (TLR) were identified as critical regulators of innate immunity to a variety of microbes, including viruses. We have rec...

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Detalles Bibliográficos
Autores principales: Velayutham, Thangam Sudha, Kolli, Deepthi, Ivanciuc, Teodora, Garofalo, Roberto P., Casola, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812158/
https://www.ncbi.nlm.nih.gov/pubmed/24205331
http://dx.doi.org/10.1371/journal.pone.0078849