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The Fosfomycin Resistance Gene fosB3 Is Located on a Transferable, Extrachromosomal Circular Intermediate in Clinical Enterococcus faecium Isolates

Some VanM-type vancomycin-resistant Enterococcus faecium isolates from China are also resistant to fosfomycin. To investigate the mechanism of fosfomycin resistance in these clinical isolates, antimicrobial susceptibility testing, filter-mating, Illumina/Solexa sequencing, inverse PCR and fosfomycin...

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Detalles Bibliográficos
Autores principales: Xu, Xiaogang, Chen, Chunhui, Lin, Dongfang, Guo, Qinglan, Hu, Fupin, Zhu, Demei, Li, Guanghui, Wang, Minggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812183/
https://www.ncbi.nlm.nih.gov/pubmed/24205114
http://dx.doi.org/10.1371/journal.pone.0078106