Biological insights into BRAF(V600) mutations in melanoma patient: Not mere therapeutic targets

Some experimental evidence indicates that uncommon BRAF mutations consisting in the substitution of 2 adjacent nucleotides within codon 600 are in a cis configuration and associate with BRAF gene amplification. These findings suggest that BRAF(V600) mutations are unlikely to occur as homozygous alte...

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Detalles Bibliográficos
Autores principales: Improta, Giuseppina, Pelosi, Giuseppe, Tamborini, Elena, Donia, Marco, Santinami, Mario, de Braud, Filippo, Fraggetta, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812198/
https://www.ncbi.nlm.nih.gov/pubmed/24179707
http://dx.doi.org/10.4161/onci.25594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812198/
https://www.ncbi.nlm.nih.gov/pubmed/24179707
http://dx.doi.org/10.4161/onci.25594

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