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Phospholipase A(2) in Experimental Allergic Bronchitis: A Lesson from Mouse and Rat Models

BACKGROUND: Phospholipases A(2) (PLA(2)) hydrolyzes phospholipids, initiating the production of inflammatory lipid mediators. We have previously shown that in rats, sPLA(2) and cPLA(2) play opposing roles in the pathophysiology of ovalbumin (OVA)-induced experimental allergic bronchitis (OVA-EAB), a...

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Detalles Bibliográficos
Autores principales: Mruwat, Rufayda, Yedgar, Saul, Lavon, Iris, Ariel, Amiram, Krimsky, Miron, Shoseyov, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812210/
https://www.ncbi.nlm.nih.gov/pubmed/24204651
http://dx.doi.org/10.1371/journal.pone.0076641