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Phospholipase A(2) in Experimental Allergic Bronchitis: A Lesson from Mouse and Rat Models
BACKGROUND: Phospholipases A(2) (PLA(2)) hydrolyzes phospholipids, initiating the production of inflammatory lipid mediators. We have previously shown that in rats, sPLA(2) and cPLA(2) play opposing roles in the pathophysiology of ovalbumin (OVA)-induced experimental allergic bronchitis (OVA-EAB), a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812210/ https://www.ncbi.nlm.nih.gov/pubmed/24204651 http://dx.doi.org/10.1371/journal.pone.0076641 |