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Functional Genetic Polymorphisms in PP2A Subunit Genes Confer Increased Risks of Lung Cancer in Southern and Eastern Chinese

Protein phosphatase-2A (PP2A) is one of the major cellular serine-threonine phosphatases and functions as a tumor suppressor that negatively regulates the activity of some oncogenic kinases. Recent studies have reported that PP2A expression was suppressed during lung carcinogenesis, we there hypothe...

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Detalles Bibliográficos
Autores principales: Yang, Rongrong, Yang, Lei, Qiu, Fuman, Zhang, Lisha, Wang, Hui, Yang, Xiaorong, Deng, Jieqiong, Fang, Wenxiang, Zhou, Yifeng, Lu, Jiachun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812212/
https://www.ncbi.nlm.nih.gov/pubmed/24204789
http://dx.doi.org/10.1371/journal.pone.0077285