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Dampening of expression oscillations by synchronous regulation of a microRNA and its target

The complexity of metazoan organisms requires precise spatiotemporal regulation of gene expression during development. We find that in the nematode Caenorhabditis elegans approximately 2,000 transcripts undergo expression oscillations synchronized with larval transitions while thousands of genes are...

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Detalles Bibliográficos
Autores principales: Kim, Dong hyun, Grün, Dominic, van Oudenaarden, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812263/
https://www.ncbi.nlm.nih.gov/pubmed/24036951
http://dx.doi.org/10.1038/ng.2763