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Development of a novel and efficient cell culture flocculation process using a stimulus responsive polymer to streamline antibody purification processes

Recent advances in mammalian cell culture processes have significantly increased product titers, but have also resulted in substantial increases in cell density and cellular debris as well as process and product related impurities. As such, with improvements in titer, corresponding improvements in d...

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Detalles Bibliográficos
Autores principales: Kang, Yun (Kenneth), Hamzik, James, Felo, Michael, Qi, Bo, Lee, Julia, Ng, Stanley, Liebisch, Gregory, Shanehsaz, Behnam, Singh, Nripen, Persaud, Kris, Ludwig, Dale L, Balderes, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812681/
https://www.ncbi.nlm.nih.gov/pubmed/23740533
http://dx.doi.org/10.1002/bit.24969