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Development of a novel and efficient cell culture flocculation process using a stimulus responsive polymer to streamline antibody purification processes
Recent advances in mammalian cell culture processes have significantly increased product titers, but have also resulted in substantial increases in cell density and cellular debris as well as process and product related impurities. As such, with improvements in titer, corresponding improvements in d...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wiley Periodicals
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812681/ https://www.ncbi.nlm.nih.gov/pubmed/23740533 http://dx.doi.org/10.1002/bit.24969 |