Factor H-Dependent Alternative Pathway Inhibition Mediated by Porin B Contributes to Virulence of Neisseria meningitidis

The identification of “factor H binding protein (fHbp)-null” invasive meningococcal isolates and the realization that widespread use of fHbp-based vaccines could herald selection of such strains prompted us to characterize novel mechanisms of alternative pathway (AP) inhibition on meningococci. Of s...

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Detalles Bibliográficos
Autores principales: Lewis, Lisa A., Vu, David M., Vasudhev, Shreekant, Shaughnessy, Jutamas, Granoff, Dan M., Ram, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812710/
https://www.ncbi.nlm.nih.gov/pubmed/24129254
http://dx.doi.org/10.1128/mBio.00339-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812710/
https://www.ncbi.nlm.nih.gov/pubmed/24129254
http://dx.doi.org/10.1128/mBio.00339-13

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