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Lipid droplet breakdown requires Dynamin 2 for vesiculation of autolysosomal tubules in hepatocytes

Lipid droplets (LDs) are lipid storage organelles that in hepatocytes may be catabolized by autophagy for use as an energy source, but the membrane-trafficking machinery regulating such a process is poorly characterized. We hypothesized that the large GTPase Dynamin 2 (Dyn2), well known for its invo...

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Detalles Bibliográficos
Autores principales: Schulze, Ryan J., Weller, Shaun G., Schroeder, Barbara, Krueger, Eugene W., Chi, Susan, Casey, Carol A., McNiven, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812963/
https://www.ncbi.nlm.nih.gov/pubmed/24145164
http://dx.doi.org/10.1083/jcb.201306140