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Lipid droplet breakdown requires Dynamin 2 for vesiculation of autolysosomal tubules in hepatocytes
Lipid droplets (LDs) are lipid storage organelles that in hepatocytes may be catabolized by autophagy for use as an energy source, but the membrane-trafficking machinery regulating such a process is poorly characterized. We hypothesized that the large GTPase Dynamin 2 (Dyn2), well known for its invo...
Autores principales: | Schulze, Ryan J., Weller, Shaun G., Schroeder, Barbara, Krueger, Eugene W., Chi, Susan, Casey, Carol A., McNiven, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812963/ https://www.ncbi.nlm.nih.gov/pubmed/24145164 http://dx.doi.org/10.1083/jcb.201306140 |
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