Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95

Although histone H3 lysine 4 (H3K4) methylation is widely associated with gene activation, direct evidence for its causal role in transcription, through specific MLL family members, is scarce. Here we have purified a human MLL2 (Kmt2b) complex that is highly active in H3K4 methylation and chromatin...

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Detalles Bibliográficos
Autores principales: Jiang, Hao, Lu, Xiangdong, Shimada, Miho, Dou, Yali, Tang, Zhanyun, Roeder, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813012/
https://www.ncbi.nlm.nih.gov/pubmed/23995757
http://dx.doi.org/10.1038/nsmb.2656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813012/
https://www.ncbi.nlm.nih.gov/pubmed/23995757
http://dx.doi.org/10.1038/nsmb.2656

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