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Anti-inflammatory Effects of Oxymatrine Through Inhibition of Nuclear Factor–kappa B and Mitogen-activated Protein Kinase Activation in Lipopolysaccharide-induced BV2 Microglia Cells

Oxymatrine, a potent monosomic alkaloid extracted from Chinese herb Sophora japonica (Sophora flavescens Ait.). possesses anti-inflammatory activittyes. This study was designed to investigate the effects of oxymatrine on nuclear factor–kappa B (NF-κB) and mitogen-activated protein kinase (MAPK)-depe...

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Detalles Bibliográficos
Autores principales: Dong, Xiao-Qiao, Du, Quan, Yu, Wen-Hua, Zhang, Zu-Yong, Zhu, Qiang, Che, Zhi-Hao, Chen, Feng, Wang, Hao, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813192/
https://www.ncbi.nlm.nih.gov/pubmed/24250585