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Production and Quality Control of [(67)Ga]-DOTA-trastuzumab for Radioimmunoscintigraphy

Breast cancer radioimmunoscintigraphy targeting HER2/neu expression is a growing field of work in nuclear medicine research. In this study, trastuzumab was successively labeled with [(67)Ga] GaCl(3) after conjugation with DOTA-NHS-ester. The conjugates were purified by molecular filtration, the aver...

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Detalles Bibliográficos
Autores principales: Alirezapour, Behrooz, R. Jalilian, Amir, Bolourinovin, Fatemeh, Moradkhani, Sedigheh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813249/
https://www.ncbi.nlm.nih.gov/pubmed/24250610