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The Effect of PEG Molecular Weights on Dissolution Behavior of Simvastatin in Solid Dispersions

The purpose of the present study was to investigate the effect of polyethylene glycol (PEG) molecular weights (6000, 12000 and 20000) as solid dispersion (SD) carriers on the dissolution behavior of simvastatin. SDs with various drug : carrier ratios were prepared by solvent method and evaluated for...

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Detalles Bibliográficos
Autores principales: Bolourchian, Noushin, Mahboobian, Mohammad Mehdi, Dadashzadeh, Simin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813355/
https://www.ncbi.nlm.nih.gov/pubmed/24250667